A potent and selective AMPK activator that inhibits de novo lipogenesis

DOI: 10.1021/ml100143q

Source and publish data:

ACS Medicinal Chemistry Letters p. 478 - 482 (2010)

Update date:2022-09-26

Topics:

Authors:

Gomez-Galeno, Jorge E.

Dang, Qun

Nguyen, Thanh H.

Boyer, Serge H.

Grote, Matthew P.

Sun, Zhili

Chen, Mingwei

Craigo, William A.

Van Poelje, Paul D.

MacKenna, Deidre A.

Cable, Edward E.

Rolzin, Paul A.

Finn, Patricia D.

Chi, Bert

Linemeyer, David L.

Hecker, Scott J.

Erion, Mark D.

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Article abstract of DOI:10.1021/ml100143q

AMP-activated protein kinase (AMPK) is a heterotrimeric kinase that regulates cellular energy metabolism by affecting energy-consuming pathways such as de novo lipid biosynthesis and glucose production as well as energy-producing pathways such as lipid ox

Full text of DOI:10.1021/ml100143q

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