Journal of Heterocyclic Chemistry p. 850 - 856 (2010)
Update date:2022-09-26
Topics:
Joksovic, Milan D.
Bogdanovic, Gordana
Kojic, Vesna
Szecsenyi, Katalin Meszaros
Leovac, Vukadin M.
Jakimov, Dimitar
Trifunovic, Snezana
Markovic, Violeta
Joksovic, Ljubinka
(Chemical Equation Presented) New N-[(1,3-diphenylpyrazol-4-yl)methyl]a- amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential.
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Doi:10.1016/j.molstruc.2010.08.016
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(2012)Doi:10.1002/chem.200900313
(2009)Doi:10.1016/j.tet.2009.04.088
(2009)Doi:10.1021/ol901372m
(2009)Doi:10.1007/s11243-017-0148-6
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