Ureas from N-Chloroamidines; An Aza-Analogous Hofmann Degradation

DOI: 10.1055/s-1989-27280

Source and publish data:

Synthesis p. 443 - 444 (1989)

Update date:2022-09-26

Topics:

Authors:

Sonnenschein, Helmut

Schmitz, Ernst

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Article abstract of DOI:10.1055/s-1989-27280

N-Chlorination and subsequent treatment with alkali of suitably substituted benzamidines yields ureas with phenyl or alkyl migration.Under the same conditions, 2-iminopyrrolidine is converted into 2-oxohexahydropyrimidine with ring enlargement.

Full text of DOI:10.1055/s-1989-27280

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