Journal of Medicinal Chemistry p. 926 - 931 (1990)
Update date:2022-09-26
Topics:
Goehring
Greenwood
Nwokogu
Pisipati
Rogers
Wolfe
A series of 2-benzylglutarimides (4) and their N-methyl analogues (5) were prepared according to the Topliss scheme for the selection of benzyl substituents to maximize anticonvulsant activity. A total of 22 such compounds were subjected to initial (phase
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