Synthesis of a pentacyclic precursor to the strychnos alkaloids

DOI: 10.1021/jo00292a042

Source and publish data:

Journal of Organic Chemistry p. 1624 - 1627 (1990)

Update date:2022-08-02

Topics:

Authors:

Kraus Kraus

Thomas Thomas

Bougie Bougie

Chen Chen

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Article abstract of DOI:10.1021/jo00292a042

An advanced intermediate for the synthesis of the Strychnos alkaloids was constructed by a sequence involving an intramolecular Diels-Alder reaction, alkylation of an enol silyl ether, and conversion of the alkylation product into a pentacyclic lactam.

Full text of DOI:10.1021/jo00292a042

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