Synthesis p. 3361 - 3371 (2021)
Update date:2022-07-29
Topics: alkenes Carbon monoxide Tandem Intermolecular Palladium Catalysis Azides C-H Amidation
Gu, Zheng-Yang
Wu, Yang
Jin, Feng
Bao, Xiaoguang
Xia, Ji-Bao
An atom- and step-economic intermolecular multi-component palladium-catalyzed C-H amidation of alkenes with carbon monoxide and organic azides has been developed for the synthesis of alkenyl amides. The reaction proceeds efficiently without an ortho -directing group on the alkene substrates. Nontoxic dinitrogen is generated as the sole by-product. Computational studies and control experiments have revealed that the reaction takes place via an unexpected mechanism by tandem palladium catalysis.
View MoreShenzhen HwaGen Pharmaceutical Co., Ltd
website:http://www.rafflespt.com
Contact:+86-752-5538396
Address:Guangdong Huizhou China
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Qingdao Kylin Trading Co., Ltd.
Contact:0086-532-68979884/58972912/68972263/65/88171519
Address:Room 2308,A building International Trade Center No.230 Changjiang Middle Road of Qingdao Economic Development Zone,Shandong,China.
LIAOYANG TENGYUAN FOOD ADDITIVE FACTORY
Contact:+86-419-5807666
Address:Haodianzi village,Hanling Town,Liaoyang county
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Doi:10.1021/ol101965a
(2010)Doi:10.1007/s00706-018-2177-z
(2018)Doi:10.1016/j.cplett.2020.137455
(2020)Doi:10.1016/j.tet.2010.07.033
(2010)Doi:10.1016/j.tet.2011.05.040
(2011)Doi:10.1016/j.crci.2010.09.006
(2011)