
Tetrahedron Letters p. 3613 - 3616 (1989)
Update date:2022-08-05
Topics:
Musachio, John L.
Lever, John L.
p-Toluenesulfonate esters of (E)- and (Z)-3-(tri-n-butylstannyl)-2-propen-1-ol readily react with nucleophiles to give vinylstannanes which are substrates for rapid, efficient and stereospecific radioiododestannylation at the no-carrier-added level.This general approach is illustrated by syntheses of iodinated spiperone analogs for studies of dopamine D2 receptors.
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(1989)