Organic and Biomolecular Chemistry p. 4085 - 4089 (2010)
Update date:2022-09-26
Topics:
Nugent, Thomas C.
Umar, M. Naveed
Bibi, Ahtaram
A pyridine based 1,2-diamine containing only one stereogenic center has been identified for fast aldol reactions (16-48 h). Using 2-5 mol% of (R)- or (S)-PicAm-2, cyclohexanone (3.3 equiv) readily undergoes aldol reactions with o-, m-, and p-substituted a
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