
Heterocycles p. 1179 - 1192 (1989)
Update date:2022-08-05
Topics:
Coutrot, Philippe
Elgadi, Abdelaziz
Grison, Claude
The reaction of diethyl 1-lithio-1-chloromethylphosphonate with aromatic imines gave aziridinylphosphonates in good yields and with an high stereoselectivity.The resulting aziridines reacted with n-BuLi and led to the 2-lithiated anions which were trapped with carbon tetrachloride to give 2-chloroaziridinylphosphonates in excellent yields.
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