Regioselective addition reactions at C-2 of 3,4-dihydropyrimidinones. Synthesis and evaluation of multifunctionalized tetrahydropyrimidines

DOI: 10.1016/j.tet.2010.08.034

Source and publish data:

Tetrahedron p. 8175 - 8180 (2010)

Update date:2022-08-04

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Authors:

Singh, Kamaljit

Arora, Divya

Balzarini, Jan

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Article abstract of DOI:10.1016/j.tet.2010.08.034

Multifunctionalized tetrahydropyrimidines derivatives have been synthesized from Biginelli 3,4-dihydropyrimidin-2-(1H)-thiones (DHPMs) efficiently. The transformation includes desulfurization of DHPMs with Raney-Ni and subsequent regioselective C-2 functi

Full text of DOI:10.1016/j.tet.2010.08.034

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