Synthesis of α-Hydroxy Ketones by Samarium(II) Iodide-Mediated Coupling of Organic Halides, an Isocyanide, and Carbonyl Compounds

DOI: 10.1021/jo00058a028

Source and publish data:

Journal of Organic Chemistry p. 1458 - 1465 (1993)

Update date:2022-08-03

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Authors:

Murakami, Masahiro

Kawano, Teiji

Ito, Hajime

Ito, Yoshihiko

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Article abstract of DOI:10.1021/jo00058a028

A new strategy for the synthesis of α-hydroxy ketones by samarium(II) iodide-mediated three-component coupling of organic halides, an isocyanide, and carbonyl compounds is disclosed.An (α-iminoalkyl)samarium(III) species is generated in situ by treatment

Full text of DOI:10.1021/jo00058a028

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