Stereocontrolled Total Synthesis of (+)- and (-)-Epibatidine

DOI: 10.1021/jo00073a013

Source and publish data:

Journal of Organic Chemistry p. 5600 - 5602 (1993)

Update date:2022-08-03

Topics:

Authors:

Corey, E. J.

Loh, Teck-Peng

AchyuthaRao, Sidduri

Daley, Donnette C.

Sarshar, Sepehr

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Article abstract of DOI:10.1021/jo00073a013

The stereocontrolled total synthesis of the novel analgesic agent (-)-epibatidine (1) and its enantiomer starting with 6-chloropyridine-3-carboxaldehyxe (2) has been carried out by way of intermediates 3-10.

Full text of DOI:10.1021/jo00073a013

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