
Tetrahedron Letters p. 2925 - 2928 (2006)
Update date:2022-08-03
Topics:
Altenhoff, Gereon
Würtz, Sebastian
Glorius, Frank
A palladium-carbene catalyzed Sonogashira coupling of unactivated alkyl bromides with alkyl substituted alkynes is reported. For the first time, unactivated secondary alkyl halides were successfully employed in Sonogashira reactions.
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