Photoregulation of papain activity through anchoring photochromic azo groups to the enzyme backbone

Article abstract of DOI:10.1021/ja00009a016

The enzyme papain has been chemically modified by 4-carboxyazobenzene (1), 3-carboxyazobenzene, (2), and 2-carboxyazobenzene, (3). The activities of the modified enzymes relative to native papain and the extent of loading by the azobenzene groups have bee