Journal of Medicinal Chemistry p. 1505 - 1510 (1990)
Update date:2022-08-04
Topics: Synthesis Biological Evaluation Prodrugs
Aggarwal
Gogu
Rangan
Agrawal
A series of prodrugs of zidovudine (AZT) has been synthesized in an effort to enhance the uptake of the prodrugs by the HIV-1 infected cells and to increase the plasma half-life of AZT. The 5'-OH function of AZT was esterified with various acids in the pr
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