Bulletin of the Chemical Society of Japan p. 2725 - 2727 (1989)
Update date:2022-08-04
Topics:
Hui-Wen, Su
Hirose, Kazuo
Shirai, Kozo
Kumamoto, Takanobu
It was found that the dilithium salt (5), which was lithiated at the side-chain of 2-methyl-3-thiophenecarboxylic acid (4), was produced regioselectivity by the reaction of 4 with lithium diisopropylamide (LDA).The reactions of 5 with alkyl halides result
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