6-(1-Hydroxyalkyl)penam sulfone derivatives as inhibitors of class A and class C β-lactamases II

DOI: 10.1016/S0960-894X(99)00107-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 997 - 1002 (1999)

Update date:2022-08-03

Topics:

Authors:

Bitha, Panayota

Li, Zhong

Francisco, Gerardo D.

Yang, Youjun

Petersen, Peter J.

Lenoy, Eileen

Lin, Yang-I

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Article abstract of DOI:10.1016/S0960-894X(99)00107-9

Two stereoselective processes for the synthesis of novel 3,6- disubstituted penam sulfone derivatives were developed. One 6β-(1- hydroxyethyl) and four 6β-hydroxymethyl penam sulfone derivatives were synthesized. All four 6β-(hydroxymethyl)penam sulfone d

Full text of DOI:10.1016/S0960-894X(99)00107-9

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