NOUVELLE METHODE DE PROTECTION DU CARBOXYLE DES ACIDES a-AMINES: ESTERS 9-FLUORENYLIQUES

Article abstract of DOI:10.1016/S0040-4039(00)99258-X

The novel 9-fluorenyl esters of various L-a-aminoacids (N-protected or N-free) are easily obtained by the action of 9-diazofluorene on the aminoacid in the appropriate organic solvent.Such esters are cleanly cleaved by mild acidolysis or hydrogenolysis and can serve as amino-components in peptide synthesis.