Design of the Synthetic Route for Helical Peptides. Synthesis and Solubility of Model Peptides Having a Helical Structure

Article abstract of DOI:10.1246/bcsj.62.1976

Fragment condensations between amino- and carboxyl-components of hydrophobic decapeptides, which have a β-sheet structure in the solid state and are insoluble in DMF, NMP, and DMSO, were examined in a mixture of CH2Cl2 and TFE (4/1, v/v) using various cou