Aromatic Nucleophilic Nitrogen-Nitrogen Exchange Reaction of N,N-Dimethyl-2,4-bis(trifluoroacetyl)-1-naphthylamine with Amino Acid Derivatives: A Facile Synthesis of Fluorine-Containing 1H-Benzoindolines and 1H-Benzoindoles

Article abstract of DOI:10.1055/s-1989-27315

Aromatic nucleophilic nitrogen-nitrogen exchange reaction of N,N-dimethyl-2,4-bis(trifluoroacetyl)-1-naphthylamine 1 with some amino acid derivatives gives the corresponding N-<2,4-bis(trifluoroacetyl)-1-naphthyl>amino acid derivatives 2a-d in excellent y