Studies on the Degradation of Mevinolin and Compactin: A Formal Route to Semisynthetic Analogues

DOI: 10.1021/jo00110a051

Source and publish data:

Journal of Organic Chemistry p. 1413 - 1427 (1995)

Update date:2022-08-04

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Authors:

Clive, D. L. J.

Zhang, Chengzhi

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Article abstract of DOI:10.1021/jo00110a051

Procedures are described for degrading mevinolin (1a) and compactin (1b) into the enone 2, which is a substance that has been elaborated into 1a, 1b, and 3-ethylcompactin (1c).Consequently, 2 serves as an advanced intermediate for the construction of semi

Full text of DOI:10.1021/jo00110a051

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