New bis-lactam chiral auxiliaries for nitrile oxide cycloadditions

DOI: 10.1016/S0040-4020(01)86280-3

Source and publish data:

Tetrahedron p. 995 - 1008 (1993)

Update date:2022-08-02

Topics:

Authors:

Stack, Jeffrey A.

Heffner, Timothy A.

Geib, Steven J.

Curran, Dennis P.

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Article abstract of DOI:10.1016/S0040-4020(01)86280-3

Two "pseudoenantiomeric" bis lactam chiral auxiliaries are introduced for use in asymmetric nitrile oxide cycloaddition reactions with derived acrylimides. Outstanding selectivities in the nitrile oxide cycloadditions (99/1) are not duplicated in other re

Full text of DOI:10.1016/S0040-4020(01)86280-3

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