Synthesis of phosphorylated derivatives of sucrose: 6,6′-di- phosphonate, 6- and 6′-phosphonates, and 6,6′-di-phosphine

Article abstract of DOI:10.1080/07328303.2010.524958

Reaction of 6,6′dideoxy-6,6′di-iodo-1′,2,3,3′,4, 4′-hexa-O-benzylsucrose with triethyl phosphite afforded the corresponding 6,6′-diphosphonate. Selective phosphonylation either at the C-6 or 6-6′ position was also possible providing the corresponding sucrose mono-phosphonates. Reaction of 6,6′-dichloro-hexa-O-benzylsucrose with diphenylphoshine anion afforded the 6,6′-diphosphinosucrose. Copyright Taylor & Francis Group, LLC.