A SYNTHESIS OF (-)-DEOXYPODOCARPIC ACID METHYL ESTER VIA AN ENZYMATIC ENANTIOSELECTIVE HYDROLYSIS OF THE KEY INTERMEDIATE ENOL ESTER

Article abstract of DOI:10.1016/S0040-4020(01)85126-7

(1R,4aR,10aS)-(-)-1-Methoxycarbonyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene (deoxypodocarpic acid methyl ester 1), a useful intermediate for the synthesis of various diterpenes, was synthesized from (R)-(+)-6-ethoxycarbonyl-2,6-dimethyl-1-