
Tetrahedron p. 1191 - 1204 (1991)
Update date:2022-07-29
Topics:
Suga, Akira
Sugiyama, Toru
Otsuka, Masami
Ohno, Masaji
Sugiura, Yukio
Maeda, Kenji
A synthetic model for the metal binding site of bleomycin with 4-dimethylaminopyridine nucleus, namely PYML-8, shows dioxygen activation up to 125percent of that of bleomycin. β-Methylstyrene is oxidized with the Fe(III)-H2O2, Fe(III)-PhIO, or Fe(II)-O2 complex systems of PYML-8 to give a set of products including optically active epoxide.The product composition is dependent on iron, oxygen source, and reducing agent employed, suggesting varied active species generated from each complex system.
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