Synthesis and Biological Activities of Novel 5-(2-Acylethynyl)uracils

DOI: 10.1021/jm00169a026

Source and publish data:

Journal of Medicinal Chemistry p. 1975 - 1979 (1990)

Update date:2022-09-26

Topics:

Authors:

Kundu, Nitya G.

Das, Biswajit

Spears, C. Paul

Majumdar, Anjali

Kang, Sang-Ihn

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00169a026

5-(2-Acylethynyl)-2,4-dimethoxypyrimidines (3-6) were synthesized in excellent yields from 2,4-dimethoxy-5-<2-(trimethylsilyl)ethynyl>pyrimidine (2) by treatment with acid chlorides in the presence of anhydrous aluminum chloride.Compounds 3-6 were deblock

Full text of DOI:10.1021/jm00169a026

Products guided by the article

Product name:5-<2-(o-chlorobenzoyl)-1-iodovinyl>uracil

Cas No:126898-89-3

R&D Labs maybe for 126898-89-3

Hangzhou Mole's Science & Technology Co.,Ltd.(expird)

Contact:+86-571-56880228

Address:15F Guodu development Building, NO.182 Zhaohui Road
Hangzhou Ledun Technology Co.,Ltd.

Contact:86-571-18767088918

Address:No.6 street,XiaSha,Hangzhou,China.
Chengdu Green technology Co.,Ltd.

Contact:86-28-82608355

Address:C9 ,Economic Headquarters, Economic Development Zone, Chengdu.
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China

Relevant to this article

Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel"

Doi:10.1039/c7ob02828h
(2018)
A New Route to the Previously Unattainable 2-Arylpyrido<2,3-b><1,5>thiazepin-4(5H)-ones

Doi:10.1021/jo00301a025
(1990)
Synthesis of [1,2,4]-triazolo[1,5-a]pyrimidines by Dimroth rearrangement of [1,2,4]-triazolo[4,3-a]pyrimidines: A theoretical and NMR study

Doi:10.1016/j.molstruc.2010.11.054
(2011)
NOVAL SYNTHESIS OF 1,3,5-TRISELENANES FROM ALDEHYDES, AND NOVEL GENERATION OF SELENOALDEHYDES BY FRAGMENTATION OF 1,3,5-TRISELENANES

Doi:10.1016/S0040-4039(01)93851-1
(1989)
PHENYLCAMPHORIC ACID: STEREOCHEMISTRY AND EPIMERIZATION

Doi:10.1016/S0040-4039(00)81949-8
(1983)
Formal <3+2> Cycloaddition of Benzylic Cations with Alkenes

Doi:10.1021/jo00048a029
(1992)

Article Doi