Tetrahedron Letters p. 5489 - 5492 (1989)
Update date:2022-08-03
Topics:
Grigg, Ronald
Markandu, Jasothara
Regiospecific nucleophilic substitution reactions involving attack of the nitrogen atom of oximes on epoxides are used to generate nitrones which are then trapped in 1,3-dipolar cycloaddition reactions.These tandem processes are shown to be flexible and to have wide synthetic scope for the construction of complex molecular frameworks.
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