Journal of Medicinal Chemistry p. 1874 - 1879 (1990)
Update date:2022-08-04
Topics:
Kawasaki, Andrew M.
Knapp, Richard J.
Kramer, Thomas H.
Wire, William S.
Vasquez, Olga S.
et al.
We have designed and synthesized several cyclic disulfide-containing peptide analogues of dynorphin A (Dyn A) which are conformationally constrained in the putative "address" segment of the opioid ligand.Several of these Dyn A analogues exhibit unexpected
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