Design and Synthesis of Highly Potent and Selective Cyclic Dynorphin A Analogues

DOI: 10.1021/jm00169a007

Source and publish data:

Journal of Medicinal Chemistry p. 1874 - 1879 (1990)

Update date:2022-08-04

Topics:

Authors:

Kawasaki, Andrew M.

Knapp, Richard J.

Kramer, Thomas H.

Wire, William S.

Vasquez, Olga S.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00169a007

We have designed and synthesized several cyclic disulfide-containing peptide analogues of dynorphin A (Dyn A) which are conformationally constrained in the putative "address" segment of the opioid ligand.Several of these Dyn A analogues exhibit unexpected

Full text of DOI:10.1021/jm00169a007

Products guided by the article

Product name:C₅₄H₈₃N₂₁O₁₂S₂

Cas No:127103-90-6

R&D Labs maybe for 127103-90-6

Tractus Company Limited

Contact:+852-8198 2399

Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Suzhou Jingye Medicine & Chemical Co., Ltd

website:http://www.jingyechem.cn

Contact:+86-512-66658588

Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Jiangsu Mingchem Corporation

website:http://www.mingchem.com/en/index

Contact:0519-85170101-802

Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou

Relevant to this article

Fused Polycyclic Aromatics via Electrophile-Induced Cyclization Reactions: Application to the Synthesis of Graphite Ribbons

Doi:10.1021/ja00096a056
(1994)
Synthesis of decalin type chiral synthons based on enzymatic functionalisation and their application to the synthesis of (-)-ambrox and (+)-zonarol

Doi:10.1016/S0957-4166(98)00172-4
(1998)
Asymmetric synthesis of chiral sulfoxides and sulfinimines by using N-sulfinylsultam

Doi:10.1016/S0040-4039(97)00472-3
(1997)
Thermal [2 + 2] cycloadditions between diphosphene complexes and alkynes

Doi:10.1021/om961072v
(1997)
Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Anti- and Syn-β-Amino Alcohols with Functionalized Allyl Groups

Doi:10.1055/s-1997-804
(1997)
Stereoselective alkylation of sulfoxides and sulfones derived from (R)-cysteine

Doi:10.1002/jlac.199719970533
(1997)

Article Doi