Synlett p. 353 - 354 (1997)
Update date:2022-08-04
Topics:
Hanessian, Stephen
Park, Haeil
Yang, Rui-Yang
Anti-β-amino alcohols with differently substituted allyl groups were obtained in high chemical yields and in good to excellent diastereoselectivities via Zn-mediated allylation of 2-(dibenzyl-amino)aldehydes in aqueous media. Swern oxidation, and reduction with NaBH4 gave enantiopure syn-β-amino alcohols in good yields.
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