Journal of Medicinal Chemistry p. 1797 - 1800 (1990)
Update date:2022-07-31
Topics:
Kim, Choung Un
Luh, Bing Yu
Martin, John C.
The synthesis of (S)-9-<4-hydroxy-3-(phosphonomethoxy)butyl>guanine (3), starting from (S)-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (4), is described.Alkylation of trityl derivative 7 with (diethylphosphono)methyl triflate provided phosphonate 8, whi
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(1932)