2-azabicyclo[2.2.1]hept-5-en-3-one epoxide: A versatile intermediate for the synthesis of cyclopentyl carbocyclic 2-deoxy-, 3-deoxy- and ara- ribonucleoside analogues.

DOI: 10.1016/S0040-4039(99)01113-2

Source and publish data:

Tetrahedron Letters p. 5783 - 5786 (1999)

Update date:2022-08-05

Topics:

Authors:

Dominguez, Belen M.

Cullis, Paul M.

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Article abstract of DOI:10.1016/S0040-4039(99)01113-2

5,6-Epoxy-exo-2-azabicyclo[2.2.1]heptan-3-one has been used as a versatile intermediate in the synthesis of 2-deoxy-, 3-deoxy- and ara- cyclopentyl carbocyclic nucleosides. An efficient, short synthesis of the (+) carbocyclic thymidine 13 is reported.

Full text of DOI:10.1016/S0040-4039(99)01113-2

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