SYNTHESIS OF 1-OXABICYCLIC β-LACTAM PRECURSORS FROM 4,6-O-BENZYLIDENE-D-ALLAL

DOI: 10.1016/S0040-4020(01)89183-3

Source and publish data:

Tetrahedron p. 7195 - 7200 (1989)

Update date:2022-08-04

Topics:

Authors:

Kaluza, Zbigniew

Chmielewski, Marek

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Article abstract of DOI:10.1016/S0040-4020(01)89183-3

Cycloaddition of trichloroacetyl isocyanate to 4,6-O-benzylidene-D-allal 4 followed by N-deprotection of the adduct produces β-lactam 9 with a good yield.Subsequent N-benzylation, 4,6-O-deprotection by hydrogenolysis, and a glycolic cleavage of the vic di

Full text of DOI:10.1016/S0040-4020(01)89183-3

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