SUBSTITUTED 4-(1',2'-ALKADIENESULPHINYL)-MORPHOLINES; PREPARATION AND HYDROLYTIC DESULPHINYLATION INTO THE CORRESPONDING ALKYNES

Article abstract of DOI:10.1016/S0040-4039(01)80555-4

By the reaction with 4-morpholinesulphenyl chloride carried out in the presence of triethylamine, several substituted propargylic alcohols have been converted into the corresponding allenic sulphinamides 2.As a complementary method, the new allenic lithio-derivatives II have been prepared and efficiently alkylated with organic halides.The acid-catalysed hydrolysis or deuterolysis of the title sulphinamides 2 provide the corresponding alkynes.