SYNTHESIS OF A CARBOCYCLIC ANALOG OF QUERCETIN VIA A BARBIER REACTION

DOI: 10.1016/S0040-4039(01)93800-6

Source and publish data:

Tetrahedron Letters p. 5563 - 5566 (1989)

Update date:2022-08-03

Topics:

Authors:

Shih, Neng-Yang

Mangiaracina, Pietro

Green, Michael J.

Ganguly, Ashit K.

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Article abstract of DOI:10.1016/S0040-4039(01)93800-6

A six-step synthetic route to the carbocyclic flavonoid 2 is described.The key step involves a 1,4-addition of a tertiary bromide to a α,β-unsaturated ester by the Barbier reaction.

Full text of DOI:10.1016/S0040-4039(01)93800-6

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