Stereoselective Michael Addition of the Imines of α-Amino Esters in the Presence of Lithium Bromide/1,8-Diazabicycloundec-7-ene

Article abstract of DOI:10.1021/jo00301a037

In the presence of lithium bromide/1,8-diazabicyclo<5.4.0>undec-7-ene, methyl <(2,2-dimethylpropylidene)amino>acetate and methyl 2-<(2,2-dimethylpropylidene)amino>propanoate undergo anti- and syn-selective Michael additions with E and Z isomers of α,β-uns