Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins

DOI: 10.1021/jm00171a030

Source and publish data:

Journal of Medicinal Chemistry p. 2529 - 2535 (1990)

Update date:2022-09-26

Topics:

Authors:

Shah Shah

Brause Brause

Chandler

Finke Finke

Ashe Ashe

Weston Weston

Knight Knight

Maycock Maycock

Doherty Doherty

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00171a030

Several 3'-substituted cephalosporin sulfones were synthesized from 3-(hydroxymethyl)cephalosporin, which was prepared by Ti(OiPr)₄ hydrolysis of the corresponding acetate. A method was also developed to prepare a 3-vinylcephalosporin. Some of

Full text of DOI:10.1021/jm00171a030

Products guided by the article

Product name:1,1-dimethylethyl 3-<1-<<<(4-methoxyphenyl)methyl>oxy>carbonyl>-2-phenylethyl>-1-L-<<(aminocarbonyl)oxy>methyl>-7α-methoxy-8-oxo-5-thia-1-azabicyclo<4.2.O>oct-3-ene-2-carboxylate

Cas No:127792-56-7

R&D Labs maybe for 127792-56-7

Wuxi D-Stone International Co., Ltd.

Contact:+86-510-82740567

Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
BioBioPha Co., Ltd

Contact:+86-871-65217109

Address:132 Lanhei Road, Kunming Institute of Botany, Chinese Academy of Sciences
Rizhao Lanxing Chemical Indusrial Co.,Ltd

Contact:86-633-2616708

Address:NO.15 West road Shenglan, Lanshan district, Rizhao City
Beijing Green Guardee Technology CO,.LTD

Contact:+86-10-69706062

Address:F2 BLdj,5 No.37 Chaoqian Road
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing

Relevant to this article

A second-generation total synthesis of (+)-discodermolide: The development of a practical route using solely substrate-based stereocontrol

Doi:10.1021/jo048534w
(2005)
POLYFLUOROALKYLATION OF BROMOHETEROCYCLIC COMPOUNDS VIA PERFLUOROALKYLCOPPER INTERMEDIATES

Doi:10.1016/S0022-1139(00)81565-1
(1990)
Sultone formation from α-hydroxycyclopentanones and alkanesulfonyl chloride

Doi:10.1248/cpb.38.234
(1990)
Doi:10.1039/jr9540001297
(1954)
Designer peptide dendrimers using click reaction

Doi:10.1016/j.tet.2011.01.023
(2011)
Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(ii) compounds with sulfur and phosphorus donors

Doi:10.1039/c0dt00845a
(2011)

Article Doi