Synthesis and biochemistry of fluorescent aromatase inhibitors

DOI: 10.1016/0039-128X(90)90008-Y

Source and publish data:

Steroids p. 123 - 127 (1990)

Update date:2022-08-04

Topics:

Authors:

Chen, Hsiu-Ho

Brueggemeier, Robert W.

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Article abstract of DOI:10.1016/0039-128X(90)90008-Y

Effective aromatase inhibitors have been developed that contain aryl functionalities at the 7α-position of the steroid nucleus. The exact interactions of 7α-substituted androstenediones with the active site of aromatase is unknown. Fluorescent derivatives

Full text of DOI:10.1016/0039-128X(90)90008-Y

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Product name:7α-<4'-(2'',4''-dinitrophenyl)amino>phenylthio-4-androstene-3,17-dione

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