Organic Phosphorus Compounds. 5. (4-Benzothiazol-2-ylbenzyl)amidophosphonate as Potent Calcium Antagonistic Vasodilators

DOI: 10.1021/jm00170a024

Source and publish data:

Journal of Medicinal Chemistry p. 2192 - 2196 (1990)

Update date:2022-08-05

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Authors:

Yoshino, Kohichiro

Goto, Katsumi

Yoshiizumi, Kazuya

Morita, Tominori

Tsukamoto, Goro

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Article abstract of DOI:10.1021/jm00170a024

Structural modification of the calcium antagonist fostedil (KB-944) and their coronary vasodilator activity are described.Amidophosphonate 4a-m, lactam amidophosphonate 7a-l, and diamide dilactam 10 were prepared, and their coronary vasodilator activity w

Full text of DOI:10.1021/jm00170a024

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