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Design and synthesis of new heterocyclic Bcr-Abl inhibitors

DOI: 10.1515/HC.2010.16.2-3.123

Source and publish data:

Heterocyclic Communications p. 123 - 135 (2010)

Update date:2022-07-29

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Authors:

Chen, Yong-FeiChen, Yong-Fei

Ni, NantingNi, Nanting

Li, MinyongLi, Minyong

Xu, Peng-FeiXu, Peng-Fei

Wang, BingheWang, Binghe

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Article abstract of DOI:10.1515/HC.2010.16.2-3.123

Herein, a series of heterocyclic Bcr-Abl kinase inhibitors with different structural scaffolds were designed and synthesized. HTScan Abll kinase assay kit was used for the inhibitory test. Some modest inhibitors were obtained.

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Full text of DOI:10.1515/HC.2010.16.2-3.123

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Products guided by the article

Product name:2-(3-chlorophenylamino)-2-oxoethyl 3,6-dichlorobenzo[b]thiophene-2-carbothioate

Cas No:1281988-41-7

1281988-41-7

R&D Labs maybe for 1281988-41-7

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