
Journal of Fluorine Chemistry p. 475 - 486 (1982)
Update date:2022-08-05
Topics:
Kawa, Hajimu
Yamaguchi, Fumihiko
Ishikawa, Nobuo
Perfluoro-2-propoxypropionic acid, which was prepared by the anionic dimerization of hexafluoro-1,2-epoxypropane, was optically resolved via diastereomeric salt formation with chiral amines.The optically pure (+) and (-) perfluoro-2-propoxypropionic acids thus obtained were found to be a convenient chiral reagent for determining enantiomeric compositions of α-amino acids by means of 19F nmr analysis.
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