
Journal of Medicinal Chemistry p. 2375 - 2379 (1990)
Update date:2022-07-29
Topics:
Adams
Blake
Broadhurst
Bushnell
Hassall
Hartmann
Keech
Stratton
Thomas
A versatile and efficient synthetic route to 4-demethoxyanthracyclinones has been utilized in the preparation of a number of aglycons having 9-alkyl, 9-(hydroxylalkyl), or 9-carbamoyl substituents. Silver trifluoromethanesulfonate catalyzed coupling of th
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