Synthesis and antitumor activity of novel 4-demethoxyanthracyclines

DOI: 10.1021/jm00171a010

Source and publish data:

Journal of Medicinal Chemistry p. 2375 - 2379 (1990)

Update date:2022-07-29

Topics:

Authors:

Adams Adams

Blake Blake

Broadhurst

Bushnell

Hassall Hassall

Hartmann

Keech Keech

Stratton

Thomas Thomas

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Article abstract of DOI:10.1021/jm00171a010

A versatile and efficient synthetic route to 4-demethoxyanthracyclinones has been utilized in the preparation of a number of aglycons having 9-alkyl, 9-(hydroxylalkyl), or 9-carbamoyl substituents. Silver trifluoromethanesulfonate catalyzed coupling of th

Full text of DOI:10.1021/jm00171a010

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