Resolution, Absolute Stereochemistry, and Enantioselectivity of 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol

DOI: 10.1021/jm00170a037

Source and publish data:

Journal of Medicinal Chemistry p. 2283 - 2286 (1990)

Update date:2022-08-02

Topics:

Authors:

Kihara, Masaru

Kashimoto, Minoru

Kobayashi, Shigeru

Ishida, Yukio

Moritoki, Hideki

Taira, Zenei

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Article abstract of DOI:10.1021/jm00170a037

Racemic 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol (PI-OH) (1) was found to be an effective potentiator of the contractile response of norepinephrine (NE) on rat anococcygeus muscle.This paper describes the resolution of racemic PI-OH by an HPLC

Full text of DOI:10.1021/jm00170a037

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