Synthetic studies on quinocarcin and its related compounds. 1. Synthesis of enantiomeric pairs of the ABE ring systems of quinocarcin

DOI: 10.1016/S0040-4020(01)80641-4

Source and publish data:

Tetrahedron p. 6193 - 6208 (1994)

Update date:2022-07-31

Topics:

Authors:

Saito, Shoichi

Tamura, Osamu

Kobayashi, Yuko

Matsuda, Fuyuhiko

Katoh, Tadashi

Terashima, Shiro

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Article abstract of DOI:10.1016/S0040-4020(01)80641-4

Enantiomeric pairs of the ABE ring system (5 and ent-5) and its analogues (6, ent-6, 7, and ent-7) of quinocarcin (1), a prominent antitumor antibiotic, were synthesized in >95% ee with an aim to elucidate structure-activity relationships of 1. The key st

Full text of DOI:10.1016/S0040-4020(01)80641-4

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