
Tetrahedron p. 7729 - 7742 (1989)
Update date:2022-08-02
Topics:
Liu, Jinjun
Nakagawa, Masako
Hino, Tohru
The Pictet-Spengler(P-S) reaction of Nb-hydroxytryptamines 5 and cysteinals 6 in the presence of trifluoroacetic acid(TFA) at room temperature gave the tetracyclic compounds 7α as well as the corresponding Nb-hydroxy-β-carbolines 8.The optically active nitrones 9, isolated from the similar reaction of 5 and optically active 6, gave optically active 7α and 8.
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