Journal of the Chemical Society. Chemical communications p. 1710 - 1711 (1987)
Update date:2022-08-04
Topics:
Walker, Daniel M.
McDonald, John F.
Logusch, Eugene W.
A flexible synthesis of D,L-γ-hydroxyphosphothricin (GHPPT), a potent inhibitor of the enzyme glutamine synthetase, is described which features silicon-mediated addition of ethyl methylphosphinate to benzyl 2-benzyloxycarbonylamino-4-oxobutyrate; selectiv
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