Australian Journal of Chemistry p. 311 - 319 (1990)
Update date:2022-07-30
Topics:
Barlin, Gordon B.
Jiravinyu, Chuenjit
Syntheses are reported for a series of di-Mannich bases of 4-(7'-trifluoromethylquinazolin-4'-ylamino)phenol derived from 4-chloro-7-trifluoromethylquinazoline with the di-Mannich bases of 4-aminophenol.Some analogous quinolines were prepared similarly.When tested for antimalarial activity against Plasmodium falciparum in vitro, the quinazolines were rather less active than the corresponding quinolines.
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