Copper(II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides

DOI: 10.1039/c0cc05557c

Source and publish data:

Chemical Communications p. 3978 - 3980 (2011)

Update date:2022-07-31

Topics:

Authors:

Wang, Wenhui

Pan, Changduo

Chen, Fan

Cheng, Jiang

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Article abstract of DOI:10.1039/c0cc05557c

Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp² C-H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li₂CO₃ causes chlorination of the C-H bond to take place. The Royal Society of Chemistry.

Full text of DOI:10.1039/c0cc05557c

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