DYNAMIC ASPECTS IN THE LDA LITHIATION OF AN ARABINOFURANOSYL DERIVATIVE OF 4-ETHOXY-2-PYRIMIDONE: REGIOSELECTIVE ENTRY TO BOTH C-5 AND C-6 SUBSTITUTIONS

DOI: 10.1016/S0040-4039(00)88789-4

Source and publish data:

Tetrahedron Letters p. 1295 - 1298 (1990)

Update date:2022-07-31

Topics:

Authors:

Shimizu, Miho

Tanaka, Hiromichi

Hayakawa, Hiroyuki

Miyasaka, Tadashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88789-4

Regioselectivity (C-5 vs.C-6) in the LDA lithiation of 1-<2,3,5-tris-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl>-4-ethoxy-2-pyrimidone can be controlled simply by changing the reaction conditions, providing a route to both the 5- and 6-substituted d

Full text of DOI:10.1016/S0040-4039(00)88789-4

Products guided by the article

Product name:6-Benzoyl-1-[(2R,3S,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-4-ethoxy-1H-pyrimidin-2-one

Cas No:129436-44-8

R&D Labs maybe for 129436-44-8

Zhejiang Allied Chemical Co.,Ltd

Contact:18967038207

Address:Area A-30, High-tech Industrial Park, Quzhou, Zhejiang, China.
Jinan Jianfeng Chemical Co., Ltd

Contact:0086-531-88110457

Address:sales01(-a-t-)pharmachemm{dot}c+o+m
Anyang Double Circle Auxiliary CO.,LTD

Contact:0086-134 6082 4403

Address:dongfeng road, anyang city, henan province,china
Shenyang Xingzhenghe Chemical Co., Ltd.

Contact:024-23509232

Address:No. 33, Naner Road, Heping Dist.
Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China

Relevant to this article

Synthesis and growth regulatory activity of pyrazolesulfanyl- and isoxazolesulfanyl-1H-[1,2,4]triazoles and their azinyl derivatives

Doi:10.1002/jhet.514
(2011)
Evaluation of 1-arylpiperazine derivative of hydroxybenzamides as 5-HT _1A and 5-HT₇ serotonin receptor ligands: An experimental and molecular modeling approach

Doi:10.1002/jhet.526
(2011)
The Stereospecific Generation of Chirally Labelled Benzylic Centres in o-Prenylphenols: 1'-R- and 1'-S-<1'-³H>-Rotenonic Acid

Doi:10.1039/c39890000981
(1989)
Iminophosphorane-mediated synthesis of pyrido[2,3-d]pyrimidine derivatives

Doi:10.1055/s-1990-26908
(1990)
A CONVENIENT SYNTHESIS OF 1,3-DIARYL-1,2,3,4-TETRAHYDRO-5,7,7-TRIMETHYL-4-OXO-2-THIOXO-7H-PYRANO<2,3-d>PYRIMIDINES

Doi:10.1016/S0040-4020(01)90530-7
(1990)
The reaction of acetal-type protective groups in combination with TMSOTf and 2,2′-bipyridyl; Mild and chemoselective deprotection and direct conversion to other protective groups

Doi:10.1016/j.tet.2011.02.048
(2011)

Article Doi