4-Diazocyclohexa-2,5-dienones as photoaffinity reagents for proteins

DOI: 10.1016/S0040-4039(00)88784-5

Source and publish data:

Tetrahedron Letters p. 1275 - 1278 (1990)

Update date:2022-07-29

Topics:

Authors:

Kessler, Pascal

Ehret-Sabatier, Laurence

Goeldner, Maurice

Hirth, Christian

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Article abstract of DOI:10.1016/S0040-4039(00)88784-5

The protonated 2-(2′-N,N-diethylaminoethyl)-4-diazocyclohexa-2,5-dienone was synthesized and tested as a photoaffinity probe for the active site of acetylcholinesterase, which was efficiently inactivated.

Full text of DOI:10.1016/S0040-4039(00)88784-5

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