Synthesis p. 743 - 744 (1991)
Update date:2022-09-26
Topics:
Neyer
Ugi
The treatment of the triacylamine, methyl 4-(dibenzoyl-aminocarbonylethyl)-2-oxoazetidine-1-acetate (2), with sodium bis(trimethylsilyl)amide leads to an unprecedented Dieckmann-type ring closure to form the anion of the carbacephem derivative, methyl 3-hydroxy-1-carbacephem-4-carboxylate, (3).
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(1990)Doi:10.1021/jo00308a007
(1990)Doi:10.1248/cpb.38.1798
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